D-Serin
Product code RXSOL-19-3060-025
D-Serine is a non-essential amino acid and dextro isomer of serine with antipsychotic activity
Description
D-Serine is a non-essential amino acid and dextro isomer of serine with antipsychotic activity. D-serine is a selective full agonist at the glycine site of N-methyl-D-aspartate (NMDA)-type glutamate receptor. Hypofunction of NMDA type of neurotransmission is believed to play a major role in pathophysiology of schizophrenia, therefore, administration of D-serine and subsequent activation of NMDA receptors may alleviate psychotic tendencies.
Application
D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate.
Precautions
CAS Number 312-84-5 Synonyms NSC 77689 (R)-Serine Molecular Formula C3H7NO3 Formula Weight 105.1 Purity ≥95% Formulation A solid Solubility PBS 5 mg/mL pH 7.2