Propylene glycol is tolerated well by the skin and shouldn't cause redness or irritation. Propylene glycol is a penetration-enhancing humectant.
 

Propylene Glycol USP is a widely used ingredient in pharmaceutical, food, cosmetic, personal care, flavors and animal feed applications; an overview of typical uses of Propylene Glycol USP as below.It must be emphasized that it is the user’s responsibility to consult area and country-specific regulations for details of approved use.

1. Pharmaceuticals - Solvent for active ingredients in oral, and topical products.
    
2. Cosmetics & Personal Care - Solvent, coupling agent, carrier, emulsion stabilizer, softening agent, viscosity modifier and humectant in many types of cosmetics and personal care products such as skincare, sun care, shampoo, bath/shower products, toothpastes, mouthwashes, shaving products and baby care products.
    
3. Flavors & Fragrances - Solvent and extraction solvent of flavors and fragrances for applications in food, beverages, perfumes and cosmetics.
    
4. Food - Various applications as a direct food additive (E 1520) such as a carrier or carrier solvent for colors, emulsifiers, antioxidants and enzymes (in Europe with maximum 1 g/kg in human foodstuffs), and humectant and stabilizer in fruits, vegetables and bakery goods (except in Europe). Propylene Glycol USP is also applied in indirect contact food applications, such as a low temperature heat-transfer fluid in the brewing, dairy and ice cream industries and for food storage facilities, an equipment cleaner fluid or a solvent for printing inks.
    
5. Pet foods & Animal Feed - Humectant, emulsifier, preservative, solvent foradditives, energy source and aid for prevention of ketosis (acetonemia) in dairycattle. In EMEA a specific tailor made Propylene Glycol Animal Feed is offered forthis application.